Epidemiology and Risk Context
The epidemiology literature in ACC separates naturally into population incidence and stage at presentation, inherited or syndromic risk, and age- or geography-specific patterns that shape screening and referral.123
Research Map
Population Epidemiology of ACC
These studies define incidence, sex distribution, stage at diagnosis, and survival patterns in population or registry cohorts.123
Grouped note: Population Epidemiology of ACC
Hereditary Risk and Syndromic Context of ACC
This cluster focuses on Li-Fraumeni syndrome, Beckwith-Wiedemann spectrum, Lynch, MEN1, Carney complex, FAP, and related hereditary settings.123
Grouped note: Hereditary Risk and Syndromic Context of ACC
Age, Geography, and Detection Context in ACC
These articles cover pediatric and young-adult disease, regional clusters such as Southern Brazil, and incidental or symptomatic detection patterns that shape diagnostic timing.123
Grouped note: Age, Geography, and Detection Context in ACC
How to Read This Literature
The grouped notes below help distinguish what is known about broad population patterns from what is known about rare but clinically important hereditary contexts.123
See Also
References
Footnotes
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Adrenocortical carcinoma: a practical guide for clinicians. Lancet Diabetes Endocrinol. 2025. PMID: 40086465. Local full text: 40086465.md ↩ ↩2 ↩3 ↩4 ↩5
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Molecular epidemiology of adrenocortical tumors in southern Brazil. Mol Cell Endocrinol. 2012. PMID: 22056871. Local full text: 22056871.md ↩ ↩2 ↩3 ↩4 ↩5
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Case Report of an Adrenocortical Carcinoma Associated With Germline CHEK2 Mutation. AACE Clin Case Rep. 2019. PMID: 30623166. Local full text: 30623166.md ↩ ↩2 ↩3 ↩4 ↩5