Diagnostic Scoring and Grading Systems

ACC overview

Diagnostic scoring in ACC is most useful when the literature is separated into adult cortical algorithms, special systems for oncocytic or pediatric tumors, and the reproducibility limits of grading across expert centers.123

Diagnostic Map

Adult Histologic Scoring Systems in ACC

This note groups the Weiss family of systems, Helsinki scoring, reticulin-based approaches, and related efforts to distinguish adenoma from carcinoma in adult practice.123

Grouped note: Adult Histologic Scoring Systems in ACC

Specialized Scoring Contexts in ACC

These articles cover oncocytic, pediatric, and borderline cortical tumors where standard adult criteria can be misleading.123

Grouped note: Specialized Scoring Contexts in ACC

Grading Reproducibility and Reporting in ACC

This cluster covers interobserver agreement, WHO-era grading, and the need for structured reporting when morphology drives prognosis.123

Grouped note: Grading Reproducibility and Reporting in ACC

How to Read This Literature

The grouped notes below focus on how each system is meant to be used rather than simply listing criteria sets.123

See Also

References

Footnotes

  1. DNA cytophotometry in adrenocortical tumours: a clinicomorphological study of 66 cases.. Virchows Arch A Pathol Anat Histopathol. 1991. PMID: 1926757. Local full text: 1926757.md 2 3 4 5

  2. Cellular DNA profiles of benign and malignant adrenocortical tumors.. Am J Surg Pathol. 1990. PMID: 2403197. Local full text: 2403197.md 2 3 4 5

  3. Morphologic characteristics of benign and malignant adrenocortical tumors.. Cancer. 1985. PMID: 3967172. Local full text: 3967172.md 2 3 4 5